Directed by Kensaku Kakimoto, and written by Sugaru Miaki (novel), and Yukiko Yamamuro, Parasite in Love, follows the story of a young man, Kengo Kosaka (played by Kento Hayashi) who suffers from extreme mysophobia. Due to his disorder, he is unable to maintain a relationship with anyone.
On the other hand, high school student Hijiri Sanagi (played by Nana Komatsu) has scopophobia. Because of her fear of being stared at, she refuses to go to school.
Both Kosaka and Sanagi do not expect to find love with another person, but they meet and fall in love.