OTT movies, series to watch out for in Prime Video in September 2025

Streaming giant Prime Video has a stellar lineup of upcoming movies and web series for September. From highly anticipated superhero dramas like Gen V season 2 to hidden Italian action gems like Hotel Costiera, here are some upcoming releases that are set to unfold this fall. So get ready to explore a thrilling binge-watch ride this September 2025. Notably, you can also access these Prime Video series and movies via OTTplay Premium.

OTT series to watch on Prime Video: September 2025 edition

The Runarounds

Creator Jonas Pate brings a captivating musical drama series that follows a group of high school graduates who team up to form a rock band. Get ready to explore a tale of friendship, musical dreams, passion, love, and personal crises. The ensemble features Brooklyn Decker, Maximo Salas, Marley Aliah, Hayes MacArthur, Mark Wystrach, and Shea Pritchard.

OTT release date: September 1

Gen V Season 2

The Boys spinoff series Gen V is back with another season packed with a new story and nuanced characters. The returning cast includes Jaz Sinclair as Marie, Lizze Broadway as Emma, Maddie Phillips as Cate, Germann as Sam, Thor and Luh as Jordan Li. Set in a college, the plot of Gen V season 2 will continue from where the first season left off. The superheroes will return to the university after being locked in prison and embark on some new challenges and quests. Meanwhile stream Gen V season one on Prime Video (also via OTTplay Premium)

Also Read: Gen V Season 2 on OTT: Release date, trailer, plot, cast, what to expect, and more...

OTT release date: September 17

The Girlfriend

Helmed by Robin Wright, who also co-stars in this psychological thriller series, The Girlfriend is a gripping tale of family, relationships, love, greed, and manipulation. It is inspired by a novel of the same name and features a star-studded ensemble with Robin Wright, Olivia Cooke, Laurie Davidson, Waleed Zuaiter, and others. The story revolves around a woman with a great career, husband, and son. However, things take an unexpected twist when his son’s girlfriend enters her life.

OTT release date: September 10

Hotel Costiera

Jesse Williams headlines this action-packed drama series as a former marine named Daniel De Luca, who returns to his hometown in Italy to take up his new job but unwittingly gets tangled in a mystery of his owner’s daughter as she disappears. Will Daniel find her? Stream this Italian series to unravel the secrets.

OTT release date: September 24

The London Railway Murders

If you’re intrigued with true crime docuseries that are packed with suspenseful twists and mystery-laden narratives, then this one is a binge-worthy pick. As the name highlights, it is set in London’s backdrop and revolves around a string of chilling murders and its investigation as police, victims, and eyewitnesses team up to hunt down the real culprits.

OTT release date: September 21

FAQs:

Q. How to watch Gen V season 2?

A. Gen V Season 2 is set to drop on Prime Video on September 17, 2025. It will also be accessible via OTTplay Premium.

Q. Is Gen V Season 1 out?

A. Yes, Gen V Season 1 is out on Prime Video.

This is a developing story and will be updated with more upcoming series and movies, so stay tuned!