Top 10 storylines from Grey's Anatomy

Grey's Anatomy stars Ellen Pompeo as Meredith Grey, a surgical genius, and focuses on the personal and professional lives of the medical staff at Grey Sloan Memorial Hospital.

With the popular medical drama coming to an end after 17 seasons, here's a list of the top 10 storylines from the series that made fans laugh, cry and fall in love with the characters.

1. The patient with a bomb inside them

In the show's second season, the bomb squad was summoned as the doctors had a unique case on their hands. The episode saw Meredith put her life on the line to save her patient and the hospital. This storyline was divided into two parts and made fans distraught and tense. As much as we were relieved that Meredith survived this deadly incident, we also felt heartbroken when Dylan is walking away with the bomb; and it explodes, leading to his death.

2. When Izzie cuts an LVAD wire

Izzie's doomed love story with Denny Duquette will always be one of the most iconic storylines of the show. The episode sees Izzie take matters into her own hands and cut Denny's LVAD wise to procure him a heart quickly. However, all of Denny's options have been exhausted even after Izzie violates the law and the oath she took as a doctor to save his life. The episode is also a memorable one, as when confronted about the cut LVAD wire, Meredith, Christina, George, and Alex confess it was them who did it. They present a united front to support Izzie and save her from being cut off from the surgical program.

3. Pick me, love me, choose me

This is one of Meredith's most famous dialogues. The scene witnesses Derek having to make a difficult choice when his ex arrives in Seattle. He must decide if he wishes to save his marriage or make things work with then intern, Meredith Grey. Although Meredith tries to play it cool, it is after a surgery that she gives Derek a heartfelt speech with the words, "Pick me, love me, choose me."

4. Meredith nearly drowns

All hell breaks loose when Meredith finds herself pushed into the water while she tries to tend to patients after a ferry boat crash. She nearly dies of hyperthermia. Viewers wait with bated breath as Derek plunges into the water and takes a blue and cold Meredith to the hospital, where she flatlines.

5. Mark declares his love for Lexie

If you're a Grey's Anatomy fan, this scene would have definitely given you goosebumps. The duo got on a plane to save a pair of conjoined twins and the plane came crashing down. Lexie suffers fatal injuries and Mark declares his undying love for her.

6. You're my person

This is another iconic line from the series and gives fans friendship goals with the bond Meredith and Christina share. These two intellectual and determined women face love, loss, and heartbreak together. It is true that Christina seldom expresses her emotions, but her loyalty and love for Meredith is evident. Although the show focuses on romantic relationships, it also gives us some of the best BFF goals

7. Alex and Izzie's wedding

When Derek is unable to remove Izzie's cancerous tumour, he and Meredith arrange a wedding for her and Alex, in case she doesn't make it. It is beautiful to witness the two get their happy ending despite Izzie's terminal illness.

8. Derek's death

This is one of the scenes that defines the show. After all the couple has been through, Derek, unfortunately, dies in a car crash. The most heart-breaking part about this scene is that he narrates the mistakes the doctors tending to him are making that lead to his eventual death. Meredith is then forced to make a decision about cutting off his life support. She lays with her head on his chest as she bids him goodbye.

9. When the women of the hospital came together

This iconic scene witnessed a patient who is a victim of sexual assault dealing with her trauma. The episode tactfully deals with the matter and portrays the reality of the situation. When the patient expresses her fear of every man she sees, all the women of the hospital rally to support her. They line the hallway right up to the entrance of the operation theatre. It is touching to witness women who never knew her come together to make her feel safe and protected.

10. The post-it wedding

When Derek and Meredith's plans of getting married at city hall fail as they get caught up at work, they have a novel and ground-breaking idea. The duo makes their quirky and romantic vows to each other on a post-it note and later have it framed. This simple yet emotional scene is sure to bring tears to your eyes.