Mrs Deshpande to Pharma: 7 New OTT releases to watch this weekend (December 20-21, 2025)

From Madhuri Dixit’s serial killer avatar in Mrs Deshpande to Nivin Pauly’s web series Pharma, here are the new OTT releases to watch this weekend (December 20-21, 2025)

Mrs Deshpande, Pharma

It is a packed schedule for the digital space with a diverse range of content marking their OTT releases as 2025 is set to wind up. From Madhuri Dixit’s serial killer avatar in Mrs Deshpande to Nivin Pauly’s web series Pharma, film stars also seek to make a mark in the digital space. Raju Weds Rambai narrates a tragic love story from Telugu, while Godday Godday Chaa 2 brings a Punjabi comedy drama. Here are the new OTT releases to watch this weekend in desi languages that are available to stream on OTTplay Premium

Latest releases for weekend watch

Hindi: Mrs Deshpande

Bollywood diva Madhuri Dixit did the unthinkable as she donned a serial killer avatar for noted filmmaker Nagesh Kukunoor’s thriller series. As the police struggle to crack another murder spree, they are forced to seek the help of Seema Deshpande who is now behind bars for a sinister set of crimes. Madhuri’s performance and a thrilling plot are the highlights of this gripping series.

Also read: Mrs Deshpande review: Madhuri Dixit is brilliant, though her grit is often tested by the show's slow, atmospheric pace

Malayalam: Pharma

Another film actor testing his luck in the digital format is Malayalam star Nivin Pauly, who dives into a medical series which seeks to expose the wrongdoings in the pharmaceutical industry. Filmmaker PR Arun helms the series which features seasoned actor Rajit Kapur in a key role. For any layman concerned about their health, this Malayalam series Pharma is a must watch.

Also read: Pharma review: Nivin Pauly-PR Arun’s series will make you ponder before you pop a pill next time

Tamil: Heartiley Battery

Scientific temperament vs old-school romance is explored in the Tamil series which revolves around Sophia. She swears by science and even comes up with a way to measure love to prevent heartbreaks. But her beliefs take a hit when she comes across Sid. Guru Lakshman and Padine Kumar play the key roles in Heartiley Battery

Telugu: Raju Weds Rambai

True events from a village in Telangana form the crux of the story as the 2025 movie delves into the relationship between Raju and Rambai. But their passionate love finds strong resistance from Rambai’s father, who looks down upon Taju’s profession as a local musician as he declares that his future son-law needs to have a government job.

Kannada: Kona

Kannada cinema brings a horror comedy which revolves around a village, which had the practice of conducting animal sacrifices. But things have changed in the modern times, with a ban placed on such rituals. Still, some of the villagers insist on continuing with the ritual. Komal Kumar, Tanisha Kuppanda, and Rithvi Jagadish appear in the film.

Punjabi: Godday Godday Chaa 2

Popular actor Ammy Virk leads this Punjabi comedy-drama, which delves into the grand wedding in a bustling village. The twist is that women seek to be in charge, a move that obviously leads to resistance. The chaos is depicted with loads of comedy in Godday Godday Chaa 2, starring Tania, Gurjazz, and Nikeet Dhillon.

Gujarati: Shubhchintak

A tale of revenge, Shubhchintak revolves around Meghana who joins forces with Jignesh and Tamanna as she tries to settle scores with the wealthy businessman Dhananjay. They seek to honeytrap him, which leads to complications and consequences as a cop gets involved too. Swapnil Joshi, Manasi Parekh, and Viraf Patell lead this crime thriller.

OTT releases FAQs

Q. Which are the latest OTT releases this week?

A. The latest OTT releases this week include Madhuri Dixit-led Mrs Deshpande Nivin Pauly's web series Pharma, Tamil series Heartiley Battery, the tragic Telugu film Raju Weds Rambai, the Kannada film Kona and the Punjabi comedy-drama Godday Godday Chaa 2

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